Combination therapy with methadone and duloxetine for cancer-related pain: a retrospective study
نویسندگان
چکیده
Background: A comprehensive approach to pain management often requires multimodal therapy and a combination of medications. Oncology patients may be prescribed methadone duloxetine as single agents or in for cancer-related pain, particularly neuropathic pain. Duloxetine is also depression anxiety with cancer.
منابع مشابه
Methadone for cancer pain
Pain is one of the most common and incapacitating symptoms experienced by patients with advanced cancer. Methadone is a potent opioid with strong affinity for the μ opioid receptor. In addition to being a potent μ opioid receptor ligand, methadone blocks the N-methyl-D-aspartic acid receptor and modulates neurotransmitters involved in descending pain modulation. These 3 properties enhance analg...
متن کاملThe Effectiveness of Gestalt Therapy Exclusively and in Combination with Cognitive-behavioral Therapy on Hope and Pain Intensity in Women with Breast Cancer
Background: Breast is a sensitive organ for women. In addition to pain, breast cancer can cause many psychological problems for the patient. The aim of this study was to compare the effectiveness of Gestalt Therapy (GT) and Gestalt therapy combined with Cognitive-Behavioral Therapy (GT-CBT) on the hope and pain intensity of women with breast cancer. Methods: It was a quasi-experimental study w...
متن کاملIntrathecal Therapy for Cancer-Related Pain
OBJECTIVE The increasing incidence of cancer survivorship has shifted treatment of cancer-related pain from short-term analgesia to long-term chronic pain management. As a result, alternatives to oral analgesics, such as intrathecal therapy, may be beneficial for patients with cancer-related pain. The authors review the use of intrathecal therapy in the management of cancer-related pain. METH...
متن کاملRelationship between serum methadone concentration and cold pressor pain sensitivity in patients undergoing methadone maintenance therapy
Hyperalgesia is a common clinical phenomenon among opioid dependent patients on methadone maintenance therapy (MMT) and it may be associated with undertreated pain and/or therapeutic failure. This study aimed to investigate association between serum methadone concentration (SMC) and cold pressor pain responses. Cold pressor pain responses in 147 opioid dependent patients on MMT were assessed us...
متن کاملMortality risk of opioid substitution therapy with methadone versus buprenorphine: a retrospective cohort study.
BACKGROUND Opioid dependence increases risk of premature mortality. Opioid substitution therapy with methadone or buprenorphine reduces mortality risk, especially for drug-related overdose. Clinical guidelines recommend methadone as the first line of opioid substitution therapy. We aimed to test whether buprenorphine treatment has a lower mortality risk than does methadone treatment by comparin...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Annals of palliative medicine
سال: 2021
ISSN: ['2224-5839', '2224-5820']
DOI: https://doi.org/10.21037/apm-20-1455